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Wednesday, May 6, 2020 | History

2 edition of Mechanisms of cell-mediated cytotoxicity found in the catalog.

Mechanisms of cell-mediated cytotoxicity

France) International Workshop on Mechanisms in Cell-Mediated Cytotoxicity (1st : 1981 : Carry-le-Rouet

Mechanisms of cell-mediated cytotoxicity

by France) International Workshop on Mechanisms in Cell-Mediated Cytotoxicity (1st : 1981 : Carry-le-Rouet

  • 178 Want to read
  • 14 Currently reading

Published by Plenum Press, c1982. in New York .
Written in English

    Subjects:
  • Cellular immunity -- Congresses,
  • Cell-mediated lympholysis -- Congresses,
  • Killer cells -- Congresses,
  • Cell death -- Congresses

  • Edition Notes

    Statementedited by William R. Clark and Pierre Golstein.. --
    SeriesAdvances in experimental medicine and biology -- v. 146, Advances in experimental medicine and biology -- v. 146
    ContributionsClark, William R., 1938-, Golstein, Pierre, 1939-
    The Physical Object
    Paginationxiii, 597 p. :
    Number of Pages597
    ID Numbers
    Open LibraryOL21835837M

    Cell-mediated immunity (CMI), also known as cellular immunity, is a historical definition that now serves to distinguish immune responses that are mediated by cells at the effector phase from those mediated by antibodies in the humoral arm of the immune response. Regulation of immunity also uses a number of common mechanistic approaches involving molecular and cellular Cited by: 1. cell-mediated cytotoxicity (ADCC) SpeciÞc Vs. NonspeciÞc Cell-Mediated Immunity ¥Phagocytosis and complement activation are considered part of the innate or nonspeciÞc immune response ¥Products of the speciÞc immune response can enhance the efÞciency of these innate immune mechanisms ¥Antibodies produced by B cells can mediate classical.

    A quick Google search of "Antibody-dependent cellular cytotoxicity" yielded , hits while "Antibody-Dependent Cell-Mediated Cytotoxicity" yielded only , hits. More telling is the number of scholarly articles: Only 1 for "Antibody-Dependent Cell-Mediated Cytotoxicity" for "Antibody-dependent cellular cytotoxicity". cell-mediated cytotoxicity: [ si″to-tok-sis´ĭ-te ] 1. the degree to which an agent has specific destructive action on certain cells. 2. the possession of such destructive action, particularly in reference to lysis of cells by immune phenomena and to antineoplastic agents that selectively kill dividing cells. adj., adj cytotox´ic.

      Antibody Dependent Cell Mediated Cytotoxicity or Hypersensitivity Type II - Duration: Hussain Biol views. The Extrinsic Apoptosis (Fas / Fas Ligand).   JNK activation and cytotoxicity could be abolished by addition of antioxidants (Lunov et al., ). When the macrophage scavenging ability is compromised, further cytotoxic events may follow. When the macrophage scavenging ability is compromised, further cytotoxic events may by:


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Mechanisms of cell-mediated cytotoxicity by France) International Workshop on Mechanisms in Cell-Mediated Cytotoxicity (1st : 1981 : Carry-le-Rouet Download PDF EPUB FB2

The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, SeptemberThe Workshop brought together for the first time leading investiga­ tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity.

The symposium provided a forum for reviewing the progress that has been made in understanding the effector and regulatory mechanisms underlying natural and induced cell-mediated cytotoxicity. Topics covered range from the immunobiology of natural killer cells to the role of macrophages as regulator, accessory, and effector cells in cytotoxicity.

This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, JuneThis workshop was organized by an international committee of immunologists interested in lymphocyte cytotoxic mechanisms (G.

This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland. The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, SeptemberThe Workshop brought together for the first time leading investiga­ tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated : Paperback.

Nai-Kong V. Cheung, in Abeloff's Clinical Oncology (Fifth Edition), Immunocytokines. Cell-mediated cytotoxicity has been highly effective against tumors in vitro and in animal models.

Immunocytokineshave shown remarkable success in activating and redirecting effectors to human tumors. Most of these studies have focused on NK, natural killer T cells (NKT), or T. International Workshop on Mechanisms in Cell-Mediated Cytotoxicity (1st: Carry-le-Rouet, France).

Mechanisms of cell-mediated cytotoxicity. New York: Plenum Press, © (OCoLC) Material Type: Conference publication, Internet resource: Document Type: Book, Internet Resource: All Authors / Contributors: William R Clark.

Mechanisms of Cell-Mediated Cytotoxicity II (Advances in Experimental Medicine & Biology): Medicine & Health Science Books @ Specific topics discussed include NK cell receptors and adhesion molecules, signal transduction and activation, and mechanisms of cytotoxicity.

The book will be an excellent learning tool and reference resource for scientists, clinicians, and students.

Get this from a library. Mechanisms of cell-mediated cytotoxicity II. [Pierre Henkart; Eric Martz;] -- This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, JuneThis workshop was organized by.

Mechanisms of Cytotoxicity by NK Cells is the resulting book of a workshop focused on the studies that enhance understanding of the basic mechanisms involved in the function and regulation of NK cells. The book presents the status of knowledge of the mechanisms responsible for the cytotoxic effects of NK cells and the regulation of their Edition: 1.

This volume provides a state-of-the-art survey of developments in the field of NK cell-cancer cell interactions, activation, and oncolytic signaling. Specific topics discussed include NK cell receptors and adhesion molecules, signal transduction and activation, and mechanisms of cytotoxicity.

The bo. Cytotoxic T cells can induce target cells to undergo programmed cell death. Cells can die in either of two ways. Physical or chemical injury, such as the deprivation of oxygen that occurs in heart muscle during a heart attack, or membrane damage with antibody and complement, leads to cell disintegration or dead or necrotic tissue is taken up and degraded by Cited by: 3.

Cytotoxic T lymphocytes (CTLs) play a critical role in the immune system; they are able to recognize and destroy virally infected and tumorigenic cells.

Specific recognition of MHC class I–peptide complexes by the T cell receptor (TcR) results in precise delivery of lytic granules to the target cell, sparing neighboring cells and the CTL itself. Over the past 10 years various studies Cited by: This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, JuneThis workshop was organized by an international committee of immunologists interested in lymphocyte cytotoxic mechanisms (G.

Berke, W.R. Clark, P. Golstein, M. Hanna, P. Henkart, R. Herberman, H.R. Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system actively lyses a target cell, whose membrane-surface antigens have been bound by specific antibodies.

It is one of the mechanisms through which antibodies, as part of. Pierre Henkart is the author of Mechanisms of Cell-Mediated Cytotoxicity ( avg rating, 0 ratings, 0 reviews, published ), Mechanisms of Cell-Media.

Cytotoxic T lymphocytes (CTLs) are critical in the elimination of infected or malignant cells and are emerging as a major therapeutic target. How CTLs recognize and kill harmful cells has been characterized in vitro but little is known about these processes in the living organism.

Here we review recent insights into CTL-mediated killing with an emphasis on in vivo CTL by:   After 60 years of intense fundamental research into T cell-mediated cytotoxicity, we have gained a detailed knowledge of the cells involved, specific recognition mechanisms and post-recognition Cited by: Cytotoxicity is a highly organized multifactor process.

Here, we reviewed the apoptosis pathways induced by the two main cytotoxic lymphocyte subsets, natural killer (NK) cells and CD8+ T cells.

Intense research has been devoted over the past two decades to the elucidation of the precise molecular mechanisms by which cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells recognize and kill target cells.

Both issues have been recently discussed at the EMBO Workshop on Cell-Mediated Cytotoxicity held in Kerkrade, The Netherlands, on April 5–9,Cited by: Entdecken Sie "Mechanisms of Cell-Mediated Cytotoxicity II" von Pierre Henkart und finden Sie Ihren Buchhändler.

This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, JuneThis workshop was organized by an int.The pathogenetic role of these cells is proposed to be cell-mediated cytotoxicity in PM and IBM, but the exact mechanisms of their action are poorly understood.